Rodenticides Lethal Dose Technical Sheet by Richard Murray (R & D Manager)
Primary Poisoning being the effect that the Rodenticide has on target pest animals (rats and mice) as well as accidental bait consumption by non-target animals.
Notes:
- LD50 is the scientifically demonstrated lethal dose which results in 50% mortality of a target animal population. It is expressed as per kg liveweight of the animal and also expressed in the table as the number of rodenticide blocks consumed per target animal and consumed causing accidental poisoning of a dog.
- PCT Surefire rodent blocks contains bittering agents to help deter accidental human consumption.
- The antidote for poisoning with Brodifacoum, Bromadiolone, Coumatetralyl, and Difenacoum is Vitamin K.
- Average median block weight of PCT rodent blocks is 15 grams.
- Always use lockable rodent bait stations in areas where children, pets and wildlife are present.
- The product with the highest toxicity to rats is Brodifacoum e.g. rats have to consume 1.3 gms bait or approx 10% of one block.
- The product with the lowest toxicity to rats is Coumatetralyl e.g. rats have to consume 10.1 gms bait or approx 75% of one block.
- From a risk management perspective, if dogs are present, consider using Surefire Broma Block or Surefire Pro Formula or Surefire Couma Block to reduce the risk of poisoning
- The efficacy of coumatetralyl being a multi-feed rodenticide is characterised by a highly cumulative effect. In comparison to the single feed anticoagulants the LD50 is high for both rats and mice. The mouse is far less susceptible than the rat to an acute dose of coumatetralyl. However, due to the cumulative effect after many consecutive days of feeding the LD50 for coumatetralyl is reduced significantly for both rats and mice.
